How Many Inhalations Does It Take to Empty a Valved Holding Chamber? - An Experimental Investigation
In this study we examined how many inhalations would be required to empty a large volume versus a smaller volume VHC, using different breathing cycles to mimic both child and adult usage
A Laboratory Investigation into the Performance of a Valved Holding Chamber with the Respimat† Soft Mist Inhaler using an Adult Oropharynx Model and Breathing Simulation
The study, modeling adult use, confirmed the hypothesis that the addition of the AeroChamber Plus* Flow-Vu* VHC to the three different Respimat† SMI products did not appreciably affect delivery of the portion of each API penetrating the model carina, and therefore available for lung deposition.