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Patient Centered Considerations when Selecting an Oscillating Positive Expiratory Pressure (OPEP) Device

Efficacy is a major aspect when selecting an OPEP device for airway clearance.

This study was presented at the North American Cystic Fibrosis Conference 2022.

Dry Powder Inhalers (DPIs) vs Metered Dose Inhaler (MDI) with Valved Spacer : Using Functional Respiratory Imaging (FRI) to Assess Modelled Lung Deposition in a COPD patient

The FRI deposition profiles highlight that the MDI/AeroChamber Plus* Flow-Vu* VHC delivered a significantly greater percentage of drug to the lung region than either of the two DPIs, irrespective of flow rate.
This was reflected in much higher modelled oropharyngeal deposition for the two DPIs.
The influence of inhalation flow profile was significant for one of the DPIs.

Using Functional Respiratory Imaging (FRI) to Compare Predicted Airway Deposition Between Pressurized Metered Dose Inhaler (pMDI) with AeroChamber Plus* Flow-Vu* Valved Holding Chamber (VHC) and Two Dry Powder Inhalers (DPIs) in a COPD patient

This study was presented at the Drug Delivery to the Lungs Conference, 2022.

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