May 10, 2019

The Impact of Delay to Inhalation on Drug Delivery: A Laboratory Study Comparing Metered Dose Inhaler (MDI) and MDI / Valved Holding Chamber (VHC) Systems

Presented at ATS 2019:

  • The use of the AeroChamber Plus* Flow-Vu* VHC maximized the lung delivery of MDI medication, even after considerable inhalation delays.
  • VHC use significantly reduced the amount of medication deposited in the oropharynx.
  • When the MDI is used alone (without a VHC) it is important that actuation of the inhaler coincides with inhalation since even a 1-second delay can reduce medication delivery to the lungs by 80%.

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