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European Medical Journal: How a Novel Portable Spacer Benefits Patients with Respiratory Disease, the Healthcare System, and the Environment

Dry Powder Inhalers (DPIs) vs Metered Dose Inhaler (MDI) with Valved Spacer : Using Functional Respiratory Imaging (FRI) to Assess Modelled Lung Deposition in a COPD patient

The FRI deposition profiles highlight that the MDI/AeroChamber Plus* Flow-Vu* VHC delivered a significantly greater percentage of drug to the lung region than either of the two DPIs, irrespective of flow rate.
This was reflected in much higher modelled oropharyngeal deposition for the two DPIs.
The influence of inhalation flow profile was significant for one of the DPIs.

Using Functional Respiratory Imaging (FRI) to Compare Predicted Airway Deposition Between Pressurized Metered Dose Inhaler (pMDI) with AeroChamber Plus* Flow-Vu* Valved Holding Chamber (VHC) and Two Dry Powder Inhalers (DPIs) in a COPD patient

This study was presented at the Drug Delivery to the Lungs Conference, 2022.