Use of a Sectional Adult Nasal Airway Model for the Evaluation of Nasal Delivery Devices and Administration Techniques

Conclusions

• The LD-based water droplet size distribution data together with the budesonide recovery from Model 2 helped confirm the visual observations with the transparent Model 1 that showed the bulk of the deposition occurred in the middle/turbinate region of the nose model
• These adult models are likely suitable for further investigations into regional deposition of inhaled sprays via the nasal route