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DDL Conference 2025

Patient Centered Considerations when Selecting an Oscillating Positive Expiratory Pressure (OPEP) Device

Efficacy is a major aspect when selecting an OPEP device for airway clearance.

This study was presented at the North American Cystic Fibrosis Conference 2022.

Using Functional Respiratory Imaging (FRI) to Compare Predicted Airway Deposition Between Pressurized Metered Dose Inhaler (pMDI) with AeroChamber Plus* Flow-Vu* Valved Holding Chamber (VHC) and Two Dry Powder Inhalers (DPIs) in a COPD patient

This study was presented at the Drug Delivery to the Lungs Conference, 2022.

Assessment of Potential Mouth/Throat Deposition and Lung Delivery of Suspension and Solution-Formulated Inhaled Corticosteroid Formulations Delivered by Pressurized Metered Dose Inhaler without and with Valved Holding Chamber Using an Anatomic Adult Up

Summary:

Presented at DDL 2017 in Edinburgh

Valved holding chambers are widely prescribed to assist patients receiving inhaled medications by avoiding losses caused by imperfect coordination of inhalation and actuation and also to reduce oropharyngeal deposition.
Regardless of whether using a solution based formulation (like Qvar) or a suspension formulation (Flovent), the use of a valved holding chamber reduced the amount of medication deposited in the mouth (oropharynx) and increased the potential for lung delivery
This study can be used to help demonstrate the value of using a valved holding chamber for both solution and suspension formulated metered dose inhalers and for all patient populations, including adults