Rationale
- Oscillating Positive Expiratory Pressure (OPEP) devices generate positive pressure pulses in the airways.
- By mobilizing and clearing mucus, OPEP therapy has the potential to induce changes in airways ventilation and subsequent drug deposition.
- There is a scarcity of published evidence though linking laboratory performance characteristics to physiological effects and clinical impact.
- A specific OPEP device is reviewed in such context in order to provide a more wholistic understanding